- It doesn't matter who you love, it's that you love. Who cares if men marry men or women marry women? In San Francisco you don't care, and I applaud that. And I applaud Mayor Newsom for being so brave.
- Upon receiving GLAAD's Golden Gate Award, which honors a member of the entertainment or media community for their outstanding contribution in combating homophobia
- See, I thought that Jay has had too many high class, very hoity-toity guests on this week. And I wanted to bring everything down a notch or two.
- Appearing on "The Tonight Show With Jay Leno"
- "He's kicking such major ass that it's insane!"
- On Tony Bennett
- It is no big deal to me. I have always been attracted to women, and I went on dates with women if they asked me.... It did not seem that different to me. But then I met my [husband], and now he is the apple of my eye.
- I consider myself bisexual, and my philosophy is, everyone innately is, although I've never had a full-on relationship with a woman, just a couple of what I'd term half-assed dalliances. So I haven't explored it to the degree that I'd like to, but I'll tell you, I'm open to it. And I don't have any problem saying that.
- [Madonna] worked so hard that it was really very touching. She’s a perfectionist and there’s never been anyone on the show that wanted to rehearse more than Madonna did. She wanted to rehearse her scenes over and over again.
- Chicago is my favorite American city. ... I like all the museums. I love the Art Institute. I love all the theatre and the blues clubs and bars, and the people are so great. I think Chicago is the perfect blend of a big city with a Midwestern finish on it. Everybody is really nice but it is a sophisticated city. I love the park. I love the zoo. I love the lake. The whole thing.
- I like to take chances, and that's the key to comedy -- dancing like an idiot but doing it with wild abandon.
- I said, `Now, wait a minute, so you're telling me you want this fish who lives in a fish tank in a dentist's office to be a fictitious character from an NBC sitcom?' I mean, it just doesn't make any sense to me. It's like, why would you want Mickey Mouse to be the lead in the `House of the Seven Gables' or something.
- On being fired from "Finding Nemo" for refusing to do her Karen voice
- I couldn't pronounce my last name until I was, like, 11.
- Well, I was missing my earplugs. And the way that I found out why they're missing is because the little Elmo -- his five pounds -- came in to the bedroom and deposited something on -- he came in from outside, he put something on the rug and was going to eat it. And I walked over and it was an earplug that had already been in and back out -- and apparently so delicious ... he wanted it again!
- On her new dog, Elmo.
- One day when I'm walking and I see -- at first I thought maybe he was resting -- but I saw a big dead seal on the beach, which was really sad. However, the thing that I thought was puzzling was there was a couple, a young guy and a girl on a beach towel not 15 feet from this big, dead mammal, and I look up and they're waving at me, like, 'Isn't it a pretty day?' And I'm like, 'There's a big dead seal right there.' They're putting on lotion. It was just bizarre. And, curtain. I just didn't want to be at the beach anymore.
- My off-white poodle. She doesn't consider herself to be gay, but I have my hunch.
- On the gayest thing in her home.
- So I light the fire with the lighter and then I'm like, 'Now, how am I going to light the candles?' And I'm racing through the house, tearing open drawers and throwing things out of closets, looking for matches ... and I had just lit the fire with the thing!!! And then I was like, 'How did I light the fire?' So then l took the thing and lit the candles.
- I'm going to climb up this ladder, you understand, to this gate that's like this high and I'm going to pass two dogs and some bags and myself over the thing into a cab driver's arms. THAT's my plan!
- My best friend was at the grocery store standing behind these two guys in line, and one of the guys told the other that I was a man. He said, 'If you look closely, you can tell that she is,' and the other guy was like, 'Oh, my God! Now that you mention it, she is a man!'. So I'm denying that I'm a man.
- I should have my 'girl citizenship' revoked. I never get facials. I never get my nails done. I'm so busy.
- I like looser clothes, which always prompts my mom to say something classic like, 'You have such a darling figure - show it off more!'
- One tabloid had an article about how I was an irresistible sex- and man-magnet and how men flock to me. Of course, they were absolutely correct...
- I am terrified of mayonnaise. It was so bad when I was little that my friends would chase me around the house with a jar of mayonnaise and a knife.
- I've been going to the same grocery store for 13 years, and all of a sudden one day everybody was like, 'Oh, my God...'
- On sudden fame.
- You don't need someone else's approval to do what you want; just figure it out and do it, damn it!
- I'm really good at staying home all day in my pajamas because I had a [dad] who did that.
- Two days ago, I dreamt I married a 5-year-old boy. He treated me like a queen and was perfectly lovely. We took a driving trip for our honeymoon. Then it dawned on me: 'Oh my God! He doesn't have a driver's license! We could get arrested!'"
- If I weren't an actress playing a socialite, I'd have lavender hair, wear crappy vintage clothes and have tattoos. I'd be some kind of crazy lawless rebel - an alternative underground riot girl.
- People see you one way and think, 'That's not her real thing, she's just putting that on now.' But that is! That's where my creativity really resides. Where it all springs. My characters are really bizarre. They're kind of dark and not really considered great people. It all comes from the same dark place, it's just filtered through comedy.
- A lot of people come up to me and say, 'Oh God, I'm just like Karen, that's what they [tell me] at the office'. I'm like, 'You know what? The people in your office may not be giving you a compliment. You may be getting fired soon.'