On performing at Live 8 
"We don't want to murder Sgt. Pepper." (2005) (Refering to the bands duet with Paul McCartney)
On religion 
"I have no trouble with Christ, but I have trouble with a lot of Christians."
On pop music 
"For me, that term "pop" is like a candy bar. You buy it because you like it, you eat it, and then you throw it away. It has no long-term meaning or value." (1985)
On being a musician 
"I don't feel that attached to my instruments. It's almost like I'm going to dominate them in some sort of way. I don't feel like they're part of me; they stand between me and something new."
On being in U2 
"It's a very unusual thing to be in a band like this. It's like being in a street gang. And it's all very well being in a street gang when you're 16, but it's bloody weird when you're 32."
Acceptance speech at the Grammy's 
"Wow. Well on a personal level this century has been going so well for us, we finished our album, I had a little baby boy a little while ago, the whole Jubilee 2000 work has been incredible, just everything has been going great. There's also been some great breakthroughs in science, the disposible mobile phone, 3 blade razor and the female orgasmatron which is great - anyway now this . . . thanks everybody our record company has been great, our management have been great and our producer's amazing." (2001)
On U2's nineties reinvention 
"This is the nineties."
Looking Back on Achtung Baby sessions, 2002 
"There's four evil motherfuckers in U2. I think we would've broken up years ago if there'd been any pansies in the band."
On dancing 
"My room overlooks the park and yesterday during the afternoon I'd opened up all the blinds and taken back the curtains so I could look out over the park. Come nightfall, I was grooving to some rap record in my room, bopping around the room for maybe half an hour. I don't know what I was doing, just messing around...and at one stage I looked out of the window and there were about 200 people looking up, clapping, applauding my dancing. That was funny."
"I'm not sure if Irish people can dance.... except for The Edge, that is, who is our own funky chicken." (Bono on Edge's dancing)
On family 
"It's a terrible cliche, but they are the most important thing in my life. More than any album. They're where it's at." (2001) (about wife Morleigh and his children)