- The United States Senate has been hijacked by the Democratic leadership. Once again, it shows the Democrats use scare tactics. They have no convictions, they have no principles, they have no ideas. But this is the ultimate. Since I've been majority leader, I'll have to say, not with the previous Democratic leader or the current Democratic leader have ever I been slapped in the face with such an affront to the leadership of this grand institution.
- On the closing of the Senate by Minority Leader Harry Reid, November 1, 2005.
- Senate Goes Into Rare Closed Session, Fox News, November 1, 2005. 
- If Senator Reid had come to me and said, 'This is a problem,' which he never did, I would have said, 'Let's talk about it.' I would have said, 'Let's bring in the Intelligence Committee or the leaders, and let's talk about it in a civil, a dignified, a respectful way.
- Senate Goes Into Rare Closed Session, Fox News, November 1, 2005.
- Rosa Parks' bold and principled refusal to give up her seat was not an intentional attempt to change a nation, but a singular act aimed at restoring the dignity of the individual. Yet Mrs. Parks' life defined a generation and redefined a nation. Her individual act sparked a revolution that marched America closer to becoming the society grounded in freedom and individual liberty envisioned by our nation's founders. I'm humbled to represent my colleagues in this ceremony honoring Rosa Parks. While our nation must say goodbye to this inspiring leader, her life and legacy will live on in all who continue to share her passion for freedom and justice.
- On the passing of Rosa Parks
- The Associated Press, October 30, 2005.
- Avian flu, which has already killed 50 people, is only a mutation away from being transmissible from person to person. We have no immunity, no vaccines, and no cure. It is imperative that we strengthen our domestic vaccine supply, expand legal protections, encourage collaboration between the public and private sectors, and advance research and development. These initiatives will help protect us from a deadly viral outbreak that experts warn could come to our shores any day.
- On the potential for a flu pandemic.
- The Associated Press, April 12, 2005.