Acyl halide

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An acyl halide (also known as an acid halide) is a chemical compound derived from an oxoacid by replacing a hydroxyl group with a halide group.


  • Acyl chlorides are attacked by a variety of nucleophiles, the reactions leading to new carboxylic acid derivatives, ketones, and aldehydes by addition – elimination mechanisms. The reactivity of acyl halides makes them useful synthetic relay points on the way to other carbonyl derivatives.
    • K. Peter C. Vollhardt, Neil E. Schore (2011) Organic chemistry : structure and function 6th ed. Ch. 20 : Carboxylic Acid Derivatives.

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