- [After kissing Sarah goodnight] It's disgusting how much I love you.
- [On the phone to Stephen's girlfriend] Put him on the phone, bitch!
- [Officer Keeney tells her she doesn't look good] Well, you don't look so hot yourself, Officer Keeney.
- [After Officer Keeney what she meant when she said, "There were three..." on the phone] Look, my husband and I just split up and it's my first night in a new house and I admit I was a little drunk. And the sentence, if you insist on knowing, was going to be, "There are three things that I'll do for you if you come jump into bed with me." Thank God I came to my senses before I said all that, and I hung up so nobody would ever have to know what I was thinking. Unless, of course, two policemen came in the middle of the night and interrogated me.
- [Over intercom] Get the fuck out of my house!
- [Seeing the Panic Room door open] My room. Definitely my room.
- [Burnham asks her if her mother is rich] Dad's rich. Mom's just mad.
- [Knowing what her mother is thinking; referring to her father and his girlfriend] Fuck him. Fuck her, too.
- [Giving Sarah a shot of glucose] Nice house you guys got.
- [Hearing Meg clicking a striker in the panic room. To Raoul] Turn the gas off. Turn the gas off right now.
- This is what I do; if some idiot with a sledgehammer could break in do you really think I'd still have a job?
- I spent the last 12 years of my life building rooms like this specifically to keep out people like us
- [After shooting Raoul dead. To Meg and Sarah] You're gonna be okay now. [Leaves]
- '[Stephen Altman says he did not call the police] Yeah, he's telling the truth. You know how I know this? 'Cause when I do this... [points the gun at Burnham] ...people don't lie.
- [Meg smashes the video cameras with a sledgehammer] Why the hell didn't we do that?
- [While locked in the panic room with Sarah. Over intercom to Meg] You fucking bitch! You pull any shit like that again, I will fucking kill her! Do you hear me? If you step outside, I'll kill her! If I see a uniform inside this house, I'll cut her fucking throat! Do you understand?
- Junior: How do we get in to that room?
- Raoul: [Burnham laughs about it] Hey! What is funny about this?... Is this shit funny yo you?
- It was supposed to be the safest room in the house.
- Jodie Foster - Meg Altman
- Kristen Stewart - Sarah Altman
- Forest Whitaker - Burnham
- Jared Leto - Junior
- Dwight Yoakam - Raoul
- Patrick Bauchau - Stephen Altman