- In this age of cynicism, bipartisanship and personal cowardice, it’s refreshing to find a group of people willing to die for what they believe.
- Patton Oswalt 
No Reason To Complain (2006)
Werewolves and Lollipops (2007)
- Every time I'm on a TV show, and I have a [sexually explicit] line, they never say, "Don't say that! At all!" Because I wouldn't; I know you're not supposed to say that. Instead they say: "Can you find a cute, G-rated way to say that?" Okay. Cleaned-up, G-rated filth is way creepier than straight-up filth. Which is creepier: "I wanna shove my hard cock in your wet pussy", or "I'm gonna fill your hoo-hah with goof juice!" That line right there is completely G-rated. You can say that on TV. And that's fucking horrifying. ...Try saying that in bed, "I'm gonna fill your hoo-hah with goof juice," and prepare for the wintery freshness of Mace.
- If the standard for being impeached is 'getting a blowjob' or 'covering up a burglary', then shouldn't Bush have been executed by now?
- They had a class at my college called "Physics for Poets!" Hey there, theatre fags and English queers! Put on some pantaloons and a scarf and take a bracing shot of absinthe and skip on down through a field of gilly-flowers to the Physics department, where we'll teach you about the music of the spheres! Wihout using any scaaary numbers! And you can ask questions like, "Is the red planet Mercury like the crimson eye of Cerberus?" Whatever, D'Artagnan, sit the fuck down. Let's just get you through this.
- I was thinking the other day about a time machine...and the first thing I thought of doing if I actually had a time machine, is that I would go back in time to about 1993 or '94, and kill George Lucas with a shovel.
- I don't give a shit where the stuff I love comes from! I JUST LOVE THE STUFF I LOVE! Hey, do you like Angelina Jolie? Does she give you a big boner? Well, here's Jon Voight's ballsack!
- I love the fact that I grew up in Sterling, I really do. Because when you're growing up in a nondescript, soulless, boring town, you've been given a present from God. And the present is: The Test of the Small Town. And you pass that test when you go, "I'm leaving before I kill everyone and then myself." That's when you pass. You have passed. You fail when you go, "I'll get a job at the Citgo and fill my truck up for free!" Ooops, you fucked up. And the person who administers your test, year after year, until you can't take it any more until you can't take it and you leave, is the movie critic on the local news. That's the guy whose job it is to keep everything relevant and cool and important away from you. You have to get off your ass and go find it on your own initiative.
- [on KFC's Famous Bowls] I just want kind of a light brown hillock of glop. If you could put my lunch in a blender, and liquefy it, and then put it into a caulking gun and inject it right into my femoral artery, even better! But until you invent a lunch gun, I would like a failure pile in a sadness bowl!
- Hey Patton, looks like Paris Hilton's writing a book. And I go, 'She's a cunt who should die of AIDS.' They go, (nervously) 'Ah ha ha, OK! Heey!! Alright.. Um, OK, follow-up question. She's also coming out with a line of handbags,' 'As long as she gets AIDS, that's fine with me, man. If she could get cancer of the AIDS of the leukemia of the eyes, that'd be awesome. If like, a biker could fuck that into her skull...'
My Weakness Is Strong (2009)
- If another one of my Whole-Foods friends says my wife should have a home birth, I am going to punch all the soy on the planet.
- [on Barack Obama's election] Do you realize for the next four years America is gonna be a cool eighties cop flick? "Barack, get your ass in my office now! Did you balance the budget again?!" "Yeah, it was just sitting there, chief..." "You wrecked twenty cars! Senate's gonna have my ass for this." "Eh, whatever, chief." And he rides away in a Camaro on two wheels.
- The night we elected Obama, CNN had holograms. They had fucking holograms. We have Star Wars technology now. What if that means Barack is gonna to be the miracle he seems to be? What if this really is the dawning of an amazing age? He gets in there, fixes the economy, gets us out of Iraq and Afghanistan. We've got Osama Bin Laden and George Bush in dunking booths filled with urine. You can just throw apples at em all day. And then what if he starts slinging amazing future technology on us. You know suddenly we get hover boots and teleportation pills and there's floating cars everywhere. At that point, would there be like two remaining holdout racists left? Like the last two guys down in Arkansas, in their hover boots? Just going, "Yeah, there's that nigger that gave us anti-gravity. I'm gonna be late to the cross burning. My free government blowjob robot broke. Fucking bullshit. This guy's the worst president ever. Just like a black guy to give you a blowjob robot for free and it breaks after 6 years. This sucks."
- I didn't realize how bad my outlook on life is until I went on a press tour for Ratatouille and had to talk to children's magazines and children's TV shows. And I wasn't interviewed by adults — I was interviewed by actual smiling children. And I didn't realize until that point how desperately I depend on negativity and cynicism just to communicate with the outside world. It's pathetic. The Oswalt family crest should just be a pair of eyes rolling off to the side, a bag of Cheetos, and then the word "fuck". That would be our shield that you'd see retreating from the great battles of history. "Fuck this — bows and arrows? Nobody told me anything about bows and arrows, goodbye."
- I’m an atheist and I love religion. And I don’t love religion in a snarky mean-spirited way; I unabashedly, sincerely love that we have religion because if we didn’t, we wouldn’t be here right now; being all postmodern and ironic. There'd be no civilization. If no one invented religion, we'd be fucked right now.Because at the dawn of man, civilization was the biggest and the strongest...and that’s as far as we're gonna go. It was whoever was the biggest fucked, killed, ate anything they wanted. That was it! Civilization was a huge psychopath with a club going ‘I’m gonna have rape for dinner.’ That was it! That’s as far as we were gonna go. And then one of my ancestors, some weakling, said ‘Look there’s no way I can beat that guy, but what if I trick him into thinking that if he doesn’t kill and rape people while he’s down here, when he dies there’s a magic city in the clouds and he can go up and have all the cake he wants?’ Now that’s not a very well formed plan but he went and told the big psycho. And the psycho heard that and said ‘Uhh, I like cake.’ “BOOM! There you go! That was the beginning of civilization. Now we can work on fire and writing and agriculture. That’s religion. It’s the ol’ sky cake dodge; it worked! And by the way, things were great for a while. But then, what was happening then was that shit was going on all over the planet. They would just use different deserts. They would tell them about sky cookies, or sky pie, or sky baklava. So as each of these civilizations grew, they built ships; they'd go visit each other, and the one guy would walk off the boat and go,'Hey, did you hear the good news about the sky baklava?' and the first guy went,'It's CAKE, motherfucker! You're dead!'...
Finest Hour (2011)
- [On seeing Jerry Maguire with his brother, who hated it]
- In the middle of Tom Cruise's speech, there's this sudden, dramatic pull-in to his face, and there's tears in his eyes, and he says, "we live in a cynical world," and that's when my brother went, "FUCK YOU!" at the top of his... oh, my God. That was...it was such a horrible, rude thing to yell, and I was laughing so hard. I could not get the air in to make the sound of laughter. People ask me, "what is your favorite comedy of all time?" Jerry Maguire, when my brother yells, "fuck you!" at Tom Cruise. It is a 90-minute setup to one punchline. It's like not jerking off for ten years, and then painting the garage! Oh, my God, I'm seeing dead kings!
- When I was 25, all I did was just scream, "Sellout! Fucking sellouts. Corporate sellout. Industry bullshit. Meh-meh-meh." I look back on it and I realized, "oh, I was screaming 'sellout' because nobody wanted to buy what I was selling."