Smallpox was an infectious disease caused by either of two virus variants, Variola major and Variola minor.
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- During the 1960s and early 1970s health workers applied epidemiologic methods to eradicate smallpox worldwide. This was an achievement of unprecedented proportions for applied epidemiology.
- Randy M. Page; Galen E. Cole; Thomas C. Timmreck (1 January 1995). Basic Epidemiological Methods and Biostatistics: A Practical Guidebook. Jones & Bartlett Learning. p. 14. ISBN 978-0-86720-869-6.