Neville: Five years, one blown marriage each. He's the toughest son of a bitch I've ever met.
Neville: We need weapons. Do you have any silverware or cutlery?
Claire: We don't have any silverware. All we have are these--
Sean: Have you heard of Eddie Kim?
Tiffany: Who hasn't? Oh! One time I saw on of those cheesy police show remakes where he killed a guy who was a witness against him by cutting out his eyes and feeding them to wild pigs. What have you got to do with him?
Sean: I'm a witness for the prosecution.
Tiffany: Oh. That's hot!
Claire: I'm gonna miss these night flights.
Grace: I like the passengers so much better when they're unconscious.
[Grace hears a couple being killed in the bathroom but thinks they are having sex.]
Grace: Mile High Club. Those were the days.
[The screaming gets louder]
Grace: [smiling] Wow, this guy is good.
[Abruptly, the screaming stops]
Grace: Well, maybe not that good.
Neville: What was the first thing I said?
Sean: Things have changed! The plane is full of snake--God, "Do as I say and you live!"
Steven Price: Snakes don't attack, unless they're provoked. Something up there's making them go crazy, possibly some kind of drug.
Neville: Well, that's good news: snakes on crack.
Sean: It's getting hot in here.
Neville: I'm from Tennessee, I hadn't noticed.
Claire: I went through a pyromaniac phase when I was younger.
Neville: You too, huh?
[Sean reveals to the other passengers that the snakes are on the plane because he was going to testify against Eddie Kim.]
Paul: Jesus Christ. We're all dead!
Neville: Not me.
Troy: It's not a video-game. It's a flight simulator.
Neville: Is that PlayStation or Xbox?
Neville: Brakes, Troy! Put your ass into it!
Troy: Uh, this part ain't in the game!
Neville: Is crashing part of the game, huh?!
Troy: I don't know, man! I usually just hit 'reset' and start the level over!
[Neville sees that they are about to collide with a building.]
Neville: Oh shit, left! Left! Turn this big motherfucker left, Troy!
Sean: What was the first thing you ever said to me?
Neville: What the fuck does that have to do with anything?