Tom Dooley or Thomas Dooley may refer to:
- Tom Dooley (song subject}, American folk hero (actually named tom Dula), hanged in North Carolina after the Civil War; the subject of a well-known folksong.
- Thomas Anthony Dooley III (1927–1961), American physician and humanitarian who worked in Laos and Vietnam
- Tom Dooley (American football official) (born 1934)
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