The human genome is the complete set of nucleic acid sequence for humans (Homo sapiens), encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. Human genomes include both protein-coding DNA genes and noncoding DNA.
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- Nearly two centuries ago, in this room, on this floor, Thomas Jefferson and a trusted aide spread out a magnificent map, a map Jefferson had long prayed he would get to see in his lifetime.
The aide was Meriwether Lewis and the map was the product of his courageous expedition across the American frontier all the way to the Pacific. It was a map that defined the contours and forever expanded the frontiers of our continent and our imagination.
Today the world is joining us here in the East Room to behold the map of even greater significance. We are here to celebrate the completion of the first survey of the entire human genome. Without a doubt, this is the most important, most wondrous map ever produced by human kind.
- Today's announcement represents more than just an effort making triumph of science and reason. After all, when Galileo discovered he could use the tools of mathematics and mechanics to understand the motion of celestial bodies, he felt, in the words of one imminent researcher, that he had learned the language in which God recreated the universe. Today we are learning the language in which God created life. We are gaining ever more awe for the complexity, the beauty, the wonder of God's most define and sacred gift.
With this profound new knowledge, humankind is on the verge of gaining immense new power to heal. Genome science will have a real impact on all our lives and even more on the lives of our children. It will revolutionize the diagnosis, prevention and treatment of most, if not all, human diseases. In coming years, doctors increasingly will be able to cure diseases like Alzheimer's, Parkinson's, diabetes and cancer by attacking their genetic roots.
- Increasing knowledge of the human genome must never change the basic belief on which our ethics, our government, our society are founded. All of us are created equal, entitled to equal treatment under the law. After all, I believe one of the great truths to emerge from this triumphant expedition inside the human genome is that in genetic terms, all human beings, regardless of race, are more than 99.9 percent the same.
- Bill Clinton, as transcribed in "President Clinton, British Prime Minister Tony Blair Deliver Remarks on Human Genome Milestone", CNN.com, (June 26, 2000).
- What more powerful form of study of mankind could there be than to read our own instruction book? I've been privileged over the last seven years to lead an international team of more than a thousand of some of the best and brightest scientists of our current generation, some of them here in this room, who have been truly dedicated to this goal. Today we celebrate the revelation of the first draft of the human book of life.
- Most of the sequencing of the human genome by this international consortium has been done in just the last 15 months. During that time, this consortium has developed the capacity to sequence 1,000 letters of the DNA code per second, seven days a week, 24 hours a day. We have developed a map of overlapping fragments that include 97 percent of the human genome, and we have sequenced 85 percent of this.
- Francis Collins as transcribed in "President Clinton, British Prime Minister Tony Blair Deliver Remarks on Human Genome Milestone", CNN.com, (June 26, 2000).
- The human genome, like the structure of blood, air or water, was discovered, not created. There is an endless amount of information on genes that begs for further discovery, and gene patents put up unacceptable barriers to the free exchange of ideas.
- Chris Hansen, A.C.L.U. staff lawyer; as quoted in John Schwartz; Andrew Pollack (29 March 2010). "Judge Invalidates Human Gene Patent". New York Times. Retrieved on 2010-03-30.
- Liquid Snake: The Genome Soldiers. They too are his progeny, carrying on his genetic legacy. But they're different. They're digital. With the completion of the Human Genome project the mysteries of humanity were laid bare...
Thanks to father's DNA, they were able to identify more than sixty 'soldier genes' responsible for everything from strategic thinking... to the proverbial 'killer instinct'. Those 'soldier genes' were transplanted, into the membrane of Next Generation Special Forces. That's how they became the Genome Soldiers. That's right... The Genome Soldiers that you've been killing are our brothers, with the same genes as ours.
- You may be surprised to learn that your sequencers are greater than 90 percent identical to proteins in other animals. It's my belief that the basic knowledge that we're providing the world will have a profound impact on the human condition and the treatments for disease and our view on our place in the biological continuum. The genome sequence represents a new starting point for science and medicine with potential impact on every disease. Taking the example cancer, each day approximately 2,000 people die in America from cancer. As a consequence of the genome efforts that you've heard described by Dr. Collins and myself this morning and the research that will be catalyzed by this information, there is at least the potential to reduce the number of cancer deaths...
- Craig Venter, as transcribed in "President Clinton, British Prime Minister Tony Blair Deliver Remarks on Human Genome Milestone", CNN.com, (June 26, 2000).